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An injection of BOTOX is prepared by drawing into an appropriately sized sterile syringe an amount of the properly reconstituted toxin slightly greater than the intended dose.

Tell your doctor if you are pregnant, intending to become pregnant, or breastfeeding before being administered Botox because it may not be suitable for you.

This is not all the information you need to know about Botox (onabotulinumtoxinA) for safe and effective use for migraine. Review the full Botox product information here, and discuss this information and any questions you have with your doctor.

Botox and Botox Cosmetic are purified forms of botulinum toxin that when injected in tiny, controlled doses are very safe and effective at relaxing excessive muscle contraction, even though ingestion of food contaminated with C. botulinum causes botulism - an often fatal, paralytic-type illness.

In general, the initial effect of the injections is seen within three days and reaches a peak at one to two weeks post-treatment. Each treatment lasts approximately three months, following which the procedure can be repeated. At repeat treatment sessions, the dose may be increased up to two-fold if the response from the initial treatment is considered insufficient, usually defined as an effect that does not last longer than two months.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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You should not use RADIESSE® or RADIESSE® (+) if you have an allergy to any component of the product, if you have a history of severe allergies, liftera if you have a bleeding disorder, or if you are pregnant or breastfeeding. You should not use RADIESSE® (+) if you have an allergy to lidocaine or medicines like it.

Areas include the forehead, bridge of the nose, the temples, the neck, the back of the head, and just above the shoulder blades in your upper back. With each treatment you will typically receive a Perfeito of 31 injections across these sites.

There are no data on the presence of Botox in human milk or adverse effects on the developing infant. Consider the benefits of Botox versus the risks, and advise against breastfeeding unless the risk is justified.

Effects may occur hours to weeks after administration. Tell your patient to call emergency services if they experience any problems swallowing, speaking, or breathing soon after botulinum toxin administration or other symptoms indicating toxin spread, such as muscle weakness, vision changes, eyelid drooping, or loss of bladder control. Retrobulbar hemorrhages sufficient to compromise retinal circulation have occurred following the administration of Botox for strabismus. Decompress the orbit if necessary.

Must be administered by a licensed provider and reconstituted exactly as directed by the manufacturer.

Reconstituted BOTOX should be clear, colorless, and free of particulate matter. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration and whenever the solution and the container permit.

The initial listed doses of the reconstituted BOTOX typically create paralysis of the injected muscles beginning one to two days after injection and increasing in intensity during the first week. The paralysis lasts for 2-6 weeks and gradually resolves over a similar time period.

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